Bovine Spongiform Encephalopathy: Implications for the United States A Follow-up
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منابع مشابه
The Response to BSE in the United States
Since the emergence of bovine spongiform encephalopathy (BSE) in the United Kingdom in the late 1980s, the United States has implemented various measures to prevent the disease from entering the country, to prevent its spread if discovered here, and to safeguard human health. Regulatory actions included import restrictions, a ban on certain ruminant tissues in ruminant feed, and a surveillance ...
متن کاملAdaptation of the bovine spongiform encephalopathy agent to primates and comparison with Creutzfeldt-- Jakob disease: implications for human health.
There is substantial scientific evidence to support the notion that bovine spongiform encephalopathy (BSE) has contaminated human beings, causing variant Creutzfeldt-Jakob disease (vCJD). This disease has raised concerns about the possibility of an iatrogenic secondary transmission to humans, because the biological properties of the primate-adapted BSE agent are unknown. We show that (i) BSE ca...
متن کاملThe new variant of the Creutzfeldt-Jakob disease accounts for no relative increase of the Creutzfeldt-Jakob disease mortality rate in the United Kingdom; this fits ill with the new variant being the consequence of consumption of food infected with the agent of Bovine Spongiform Encephalopathy
BACKGROUND A new variant of Creutzfeldt-Jakob disease was described in the United Kingdom. It is often claimed that it is caused by consumption of food infected with the agent of bovine spongiform encephalopathy. However, this remains open to question because the number of cases of the variant is, at the present time, less than would be expected from a major food-borne source. DISCUSSION The ...
متن کاملPrion protein gene (PRNP) variants and evidence for strong purifying selection in functionally important regions of bovine exon 3.
Amino acid replacements encoded by the prion protein gene (PRNP) have been associated with transmissible and hereditary spongiform encephalopathies in mammalian species. However, an association between bovine spongiform encephalopathy (BSE) and bovine PRNP exon 3 has not been detected. Moreover, little is currently known regarding the mechanisms of evolution influencing the bovine PRNP gene. Th...
متن کاملThe emergence of bovine spongiform encephalopathy and related diseases.
Since 1986, approximately 170,000 cases of bovine spongiform encephalopathy (BSE) have occurred among approximately one million animals infected by contaminated feed in the United Kingdom. A ruminant feed ban in 1988 resulted in the rapid decline of the epidemic. Transmissible spongiform encephalopathies due to agents indistinguishable from BSE have appeared in small numbers of exotic zoo anima...
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تاریخ انتشار 1996